Up-to-date, reader-friendly and authentic textbook. • All chapters and sections have been thoroughly updated up to the last half of 2016 with newer information. • Deal with the theoretical and clinical aspects of health and diseases. • The present edition has been the concerted effort of many reputed medical teachers holding important teaching and research positions in India. • Includes treatment modalities, information on basic sciences, such as genetics, therapeutics, invasive and non-invasive interventions, instrumentation in health sciences, introduction to molecular tools in diagnosis and treatment, like specific monoclonal antibodies. • Enriched with study aids such as chapter summary and important boxes for easy learning and retention. • Tables, figures and flowcharts have been introduced wherever necessary. • Reference to the source has been included wherever new information has been added. • This textbook will serve undergraduates, postgraduate students of medicine, primary care physicians, practitioners, teaching staff of medical colleges and allied subjects of medicine, such as Ayurveda, Homeopathy, etc.