It is important for ophthalmologists to keep up to date with the most recent research and advances in their rapidly developing field. This handbook is a compilation of major clinical trials in different subspecialties in the field of ophthalmology. Each trial is presented in a uniform manner, detailing the background and purpose of the study, design, number of subjects with inclusion and exclusion criteria, outcomes, then results and conclusions. Key points Compilation of major clinical trials in ophthalmology Covers all subspecialties in the field Each trial is presented in a uniform manner to assist learning Includes extensive references for further reading