Gives balanced, dependable content on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. Includes 60 new contributing authors and 12 new chapters that cover Artificial intelligence in Cardiovascular Medicine; Influenza, Pandemics, COVID-19, and Cardiovascular Disease; Tobacco and Nicotine Products in Cardiovascular Disease; Impact of Healthcare Policy on Quality, Outcomes, and Equity in Cardiovascular Disease; Impact of the Environment on Cardiovascular Health, and more. Features a new introductory chapter, Cardiovascular Disease: Past, Present, and Future by Eugene Braunwald, MD, offering his unique, visionary approach to the field of cardiology. Provides cutting-edge coverage of key topics such as proteomics and metabolomics, TAVR, diabetocardiology, and cardio-oncology. Contains 1,850 quality illustrations, radiographic images, algorithms, and charts. Highlights the latest AHA and ACC guidelines to clearly summarize diagnostic criteria and clinical implications.